
BrightMEM™ Corneal Allograft
BrightMEM Anterior Keratoplasty (BMAK) Surgical Training Resources
The BrightMEM Corneal Allograft
BrightMEM is an innovative corneal allograft composed of Descemet’s Membrane that promotes corneal re-epithelialization and functions as a robust basement membrane with natural long-term durability – representing a new treatment for patients with impaired corneal healing.
Clinical Experience
Approximately 90% of cases reported were fully healed within a mean healing time of 34.5 days
For patients with follow-up care after 12 months, 100% reported complete re-epithelization
More than half reported improved vision within a month – and vision reportedly continues to improve with time
A successful graft retention rate of 92.7%
Significant improvement in limbal cell growth demonstrated by an improved central staining grade from 3.2+ to 2.2+
Neovascularization drops from an average of 71.4% to just 5.8%
No infectious, inflammatory or rejection complications were reported
Ideal Patients
• Non-healing corneal epithelial defect
• Herpes Zoster epitheliopathy
• Partial limbal stem cell deficiency (≤75%) with or without epithelial defect
• Post-infectious / post-operative Neurotrophic keratitis
• Chronic epitheliopathy
• Medicamentosa / toxicity / CL overuse LSCD